Birt-Hogg-Dubé Syndrome
What is Birt-Hogg-Dubé syndrome? Birt-Hogg-Dubé syndrome is a rare autosomal dominant disorder caused by a mutation in the gene FLCN, which codes for the protein folliculin. FLCN is though to act as a tumor suppressor. Birt-Hogg-Dubé syndrome is marked by the occurrence of multiple benign tumors derived from the hair follicle. Associated conditions include: Benign and malignant renal [...]